HOW DOES COLLAGEN WORK?

How does Collagen work?

Collagen is a natural fibrous protein that is already naturally found in your own bones, skin, and cartilage. As we age, collagen levels in the skin begin to decrease, leading to loss of elasticity and fullness, particularly in the face.

How Many Times Must I Be Treated?

Treatment with bovine Collagen (Zyplast®/Zyderm®) requires a test to determine if you are allergic (3-5% of people are). A wait of 1 month is required; many physicians perform a second test and wait 2 weeks since very rarely the first test is falsely negative. Newer collagen products (Cosmpolast®/Cosmoderm® and Evolence® family) do not require allergy testing. The number of individual collagen injections will vary depending on what we are treating you for. Most individuals will need to repeat injections every three months.

Are there side effects with collagen products?

Collagen is an extremely safe product with excellent track record when used in the midface, laugh lines and lips. As with all fillers, collagen can have some adverse events such as: bruising, irregularity, over/under correction and nodularity. However, compared to hyaluronic acids which will be discussed below, collagen products cause less immediate swelling. Injection is not recommended for areas under or around the eyes.

How Long Will It Last?

Injectable collagen treatments will fill in depressions or lines and augment soft tissue features, to give you a fresh, glowing, youthful look. Bovine and human-derived collagen are the shortest lasting fillers, with the duration of three months. Evolence® has been reported to last six months or longer.

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Long Term Vs. Short Term Facial Beauty treatments

Long Term Vs. Short Term Facial Beauty treatments

In general we can classify such treatments as either shorter (3-6 months) or longer (from 6-24 months) or even permanent. Which is which? In this chapter we take a look at two ways to approach facial procedures:

1. Short & Sweet – or Short-term – (3 to 12 months): Many of the treatments we offer fall into the “short and sweet” category, meaning they last for about three to six months and do require minimal upkeep to maintain their effectiveness.
2. A (Slightly) Longer Story – or Long-term – (over 12 months): Other procedures last longer and don’t require quite so many office visits to perfect.

Why two options? There are a few reasons. In the case of fillers, it may be a matter of cost (the shorter the duration, the lower the cost) or that certain fillers are not appropriate for certain areas of the face. Additionally, certain aging issues may only be addressed by certain technologies which have a specific duration of effect (e.g., loose skin treated by ThermaCool®). Another factor influencing choice is downtime (e.g., CO2 laser resurfacing vs. fractionated laser resurfacing).

Short & Sweet: 3-12 Months

In this section of Chapter 6 we discuss those facial treatments that we refer to as “short and sweet,” meaning just like your dentist or other doctors you only have to come into the office every three to six months to help maintain the youthful effect of these mostly temporary, but quite effective, treatments.
These short-term (3 to 12 month duration) treatments include:

• Botox®
• Hyaluronic Acids (Restylane®, Perlane®, Juvederm™)
• Collagen

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Injectables: How Long Will They Last?

The images above are from actual clients. Pre Artefill and Post Artefill.

Injectables: How Long Will They Last?
The Simple Answers


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“More than anything else, I’d like to be an old man with a good face, like Hitchcock or Picasso.”
~ Sean Connery

Duration of Injectable Products

This handy chart will help you determine how long a particular injectable lasts:

Short Term (3 – 12 months):

• BOTOX® (3 months)
• Collagen products
o Bovine collagen: Zyderm®, Zyplast® (3 months)
o Human-based collagen: Cosmoderm®, Cosmoplast® (3 months)
o Porcine collagen: Evolence®, Evolence® Breeze (6 months)
• Juvederm™ (6-12 months)
• Restylane® (6-12 months)
• Perlane® (6-12 months)
• Fascian™ (Extremely variable; increasing duration with repeat treatments)

Long Term (over 12 months):

• Radiesse® (1-2 years)
• Sculptra® (2-3 years)
• Artefill® (Permanent)
• Silikon® 1000 (Permanent)

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